Human mutations in Notch signalling components have been implicated in several forms of congenital cardiovascular disease, including cardiac outflow tract defects (jagged 1, notch 2), aortic valve ...

Calcific aortic stenosis is a progressive disease with no effective medical therapy that ultimately requires aortic valve replacement (AVR) for severe valve obstruction. Echocardiography is the ...

Aortic stenosis is the most common valvular disease requiring valve replacement. Valve replacement therapies have undergone progressive evolution since the 1960s. Over the last 20 years, transcatheter ...

Among patients with aortic regurgitation (AR) undergoing TAVR with the Trilogy valve, the rate of mortality at one year was 8.1%, significantly lower than the prespecified goal of 25% to show ...

AI-driven midstream reliability is transforming gas compression by improving uptime, boosting throughput, and reducing ...

Introduction: Nasal obstruction is one of the most prevalent complaints in the population. The main causes of nasal obstruction are inflammatory, infectious or anatomical alterations. Anatomical ...