In patients with the tuberous sclerosis complex, the standard of care for subependymal giant-cell astrocytomas is neurosurgical removal, but everolimus may be a therapeutic option. This drug inhibits ...
Please provide your email address to receive an email when new articles are posted on . The FDA today approved a pediatric dosage form of everolimus to treat subependymal giant cell astrocytoma. It is ...
SARC016: Phase II study of everolimus in combination with bevacizumab in sporadic and neurofibromatosis type 1 (NF1) related refractory malignant peripheral nerve sheath tumors (MPNST). This is an ...
Tuberous sclerosis complex is associated with radiologically visible abnormalities of brain structure, principally tubers and subependymal nodules. We reviewed the literature on neuroimaging of tubers ...
Subependymal giant cell astrocytoma is a benign brain tumor mostly associated with tuberous sclerosis complex. However, it may be misinterpreted as other high-grade brain tumors due to the presence of ...
A 4 year-old girl presented with seizures and a delay in motor milestones. Tuberous Sclerosis (TS): T1-weighted with gadolinium axial MRI. Note the large, enhancing subependymal nodule on the right.
In this artist's representation of the adult subependymal neurogenic niche (viewed from underneath the ependyma), electrical signals generated by the ChAT+ neuron give rise to newborn migrating ...
Neurosurgical resection is the standard treatment for subependymal giant-cell astrocytomas in patients with the tuberous sclerosis complex. An alternative may be the use of everolimus, which inhibits ...
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