Statin use in patients with primary biliary cholangitis is linked to lower risks for hepatic decompensation and major adverse liver outcomes.

The cholangitis infection is often caused by bacteria, a gallstone or any another blockage. Primary biliary cholangitis is a chronic condition where inflammation of the bile duct system keeps bile ...

—A recent study provides genetic evidence linking a higher body mass index (BMI) to an increased risk of primary biliary cholangitis and autoimmune hepatitis but a decreased risk of primary sclerosing ...

Researchers in the U.S. examined time to first hospitalization for hepatic decompensation, liver transplantation, or death in patients with PBC. A separate model tracked time outside of prespecified ...

A primary biliary cholangitis (PBC) diagnosis can be life-changing. For many, it’s an emotional journey filled with questions, uncertainties and a need to redefine what life looks like with a chronic ...

Seladelpar is an oral, selective peroxisome proliferator-activated receptor delta agonist. Treatment with seladelpar was associated with an improvement in cholestatis markers in patients with primary ...

This indication was approved under accelerated approval based on a reduction of alkaline phosphatase. The Food and Drug Administration (FDA) has granted accelerated approval to Iqirvo ® (elafibranor) ...

Seladelpar, an investigational selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ), significantly improves liver biomarkers of disease activity and bothersome symptoms of ...

Please provide your email address to receive an email when new articles are posted on . A greater percentage of patients treated with seladelpar achieved biochemical response and normalization of ...

EXTON, PA, July 17, 2025 (GLOBE NEWSWIRE) -- The treatment landscape for primary biliary cholangitis (PBC) has undergone a marked transformation over the past year, driven by the recent approvals of ...

Please provide your email address to receive an email when new articles are posted on . SAN DIEGO — Quantitative magnetic resonance cholangiopancreatography may help assess changes in the biliary tree ...

Primary biliary cholangitis (PBC) is a chronic cholestatic disorder in which symptoms exert a direct influence on patients’ ...