Nature

Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells

Src family kinases (SFKs) are a unique group of enzymes that have diverse functions in cell proliferation, survival, differentiation, adhesion and migration. They have important regulatory roles in ...
The American Journal of Managed Care

OCM PP1 True Up 1/PP2 Initial Reconciliation—Lessons Learned

CMS recently released the Oncology Care Model (OCM) performance period 1 (PP1) true-up 1 and the performance period 2 (PP2) initial reconciliation. The performance data show some practices may be ...
Nature

Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling

Resistance to chemotherapy is believed to be a major cause of treatment failure in pancreatic cancer. Thus, it is necessary to explore alternative therapeutic modalities to overcome drug resistance in ...