UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory ...

A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...

A study from FAU has shown that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell ...

In nanoscale particle research, precise control and separation have long been a bottleneck in biotechnology. Researchers at ...

Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...

Shin-Etsu Chemical Co., Ltd. (Head Office: Tokyo; President: Yasuhiko Saitoh; hereinafter, “Shin-Etsu Chemical”) and Hokkaido University (Location: Hokkaido ...

The success of mRNA vaccines has sparked significant interest and investment in using mRNA technology to treat a broad range of diseases, including cancer, infectious diseases, and rare conditions.

Ten consecutive tissue sections from a single C. elegans nematode, shown as optical images (left stack) and corresponding lipid distribution maps generated by MALDI mass spectrometry imaging (MSI) ...

Lipid nanoparticles consist of spherical vesicles made of ionizable lipids with a positive charge at a low pH level, while being neutral at a physiological pH. Such a characteristic enables RNA ...

Aircraft wing-shaped structures inside tiny channels produce consistent drug delivery particles at any scale, from small laboratory tests to factory production, while substantially cutting costs. But ...