Isocitrate dehydrogenase (IDH)-mutant gliomas happen when IDH1 or IDH2 changes create an abnormal enzyme. This mutant enzyme makes D-2 hydroxyglutarate (D-2HG), which encourages tumor growth.
Considering the caregiver in early-phase clinical trials. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.
Survival outcomes associated with first-line PCV or temozolomide in combination with radiotherapy in IDH-mutant 1p/19q-codeleted grade 3 oligodendroglioma. This is an ASCO Meeting Abstract from the ...