A team of researchers has built a new protein sequencing workflow that pairs mirror proteases with deep learning software to read peptide sequences with far greater accuracy than previous methods.

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to patient outcomes using widely available bulk RNA sequencing data. The approach ...

ctDNA test, which is an important aspect in liquid biopsy, offers a non-invasive alternative to tissue biopsies for cancer diagnosis and monitoring. Ultra-deep ctDNA sequencing enabling the detection ...

An international research team has developed a new genomic technique that can track the spread of multiple superbugs in a hospital simultaneously. In a proof-of-concept study, scientists at the ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...