Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...
We performed whole-transcriptome sequencing (n = 188) and exon capture DNA sequencing (n = 208) on pretreatment tumors from the CALGB 90601 randomized trial of gemcitabine/cisplatin plus bevacizumab ...
Validation of a 15-Gene Prognostic Signature in Metastatic Clear Cell Renal Cell Carcinoma Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ...
Cells face constant threats from inside and out. Thus, they’ve evolved sophisticated stress response pathways such as the unfolded protein response (UPR), ...
Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...
This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...
Recently, the research team led by Prof. Junjiu Huang from Sun Yat-sen University, in collaboration with Prof. Fenghua Liu’s team at Guangdong Women and Children Hospital, published a study titled ...
RIVERSIDE, Calif. -- A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings ...
Tardigrades, often called water bears or moss piglets, are microscopic creatures that can survive just about anything: boiling heat, freezing cold and crushing pressure. 2 In fact, tardigrades are the ...
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