The second messenger cyclic di-AMP (c-di-AMP) plays a pivotal role in bacterial physiology by regulating osmolyte transport, potassium uptake, cell wall integrity and the overall stress response.

G-protein coupled receptors (GPCRs) are a major class of targets for drug discovery. Cyclic AMP (cyclic adenosine 3′,5′-monophosphate) is a second messenger and one of the most important intracellular ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...

Immune cells that eat bacteria in the body don't stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells ...

A new study published in PNAS highlights a newly identified mechanism of how auditory sensitivity is regulated that could temporarily reduce sensitivity of the auditory system to protect itself from ...