The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...
(Nasdaq: XCUR), a clinical-stage biotechnology company developing therapeutics for hematologic diseases, today announced the publication of results from a prior Phase 2 clinical study evaluating ...
Neoadjuvant treatment with weekly high-dose 5-fluorouracil as a 24h-infusion, folinic acid (AIO regimen) and oxaliplatin in patients with primary resectable liver metastases of colorectal cancer: Long ...
Co-receptor tropism has been identified to correlate with HIV-1 transmission and the disease progression in patients. A molecular epidemiology investigation of co-receptor tropism is important for ...
If CXCR4 is removed from the cells, red blood cell development stops at subsequent stages, and bone marrow production drops severely. That loss helps to confirm just how important the CXCL12-CXCR4 ...
BOSTON, April 29, 2024 (GLOBE NEWSWIRE) -- X4 Pharmaceuticals (XFOR) (Nasdaq: XFOR), a company driven to improve the lives of people with rare diseases of the immune system, today announced that the U ...