Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Alcohol contributes to more than 200 health conditions, fueling a staggering 175,000 deaths each year across the U.S. Globally, the toll reaches nearly 3 million lives. Despite these alarming numbers, ...

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the brain learns that the drug is the fastest route to reward. Yet scientists still ...

A University at Buffalo neuroscientist whose focus is the brain's reward system and its role in addiction is helping to illuminate how exercise can aid the brain in addiction recovery. Over the past ...

A widely accepted assumption in the addiction field is that neuroanatomical changes observed in young people who use alcohol or other substances are largely the consequence of exposure to these ...

A shaky hand, a racing heart, a wave of dread; alcohol withdrawal can feel like your body has turned against you. For many people with alcohol use disorder, those early days without alcohol bring ...

Participants in a deep brain stimulation trial for drug addiction say the implants triggered compulsive behavior that upended ...