PURPOSE: In a randomized clinical trial in patients with advanced non–small-cell lung cancer (NSCLC), infusion with adenosine 5′-triphosphate (ATP) inhibited loss of body weight and quality of life.

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Adenosine triphosphate (ATP) is a molecule that provides crucial energy to activate a wide array of biological processes, in many organisms including the movement of muscles and the propagation of ...

The effect of Adenosine triphosphate in inhibiting glycolysis in mitochondrial extracts from pea cotyledons was studied. It was possible to show a direct inhibition of adenosine triphosphate on ...

Phase II study of gemcitabine (Gem) and trastuzumab (T) combination therapy in first line metastatic breast cancer (MBC) patients (pts) with HER2 overexpression No significant financial relationships ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

ADENOSINE triphosphate is split by recrystallized myosin into adenosine diphosphate and free phosphate ; the adenosine triphosphate used and the diphosphate formed corresponded to Lohmann's formula.

Adenosine kinase is an important enzyme that regulates both the intracellular and extracellular concentrations of adenosine. The inhibition of this enzyme has numerous clinical applications ranging ...