People often reach for a cup of coffee when they feel sluggish and need a quick pick-me-up. The expectation is that caffeine ...
Researchers at BellBrook Labs have developed a high throughput screening (HTS) assay to discover small molecule modulators for the immunosuppressive ectonucleotidase, CD73. The Transcreener ADO CD73 ...
Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine ...
The coffee paradox in adenosine-mediated antidepressant action. Depression (left) and coffee consumption (right) are both linked through adenosine signaling (center), creating a pharmacological ...